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More Evidence for Resveratrol

I've blogged about resveratrol before (here and here). It has already been shown to increase lifespan in yeast, fruit flies, and worms. Now we have the first evidence (via Fight Aging!) that it increases lifespan in vertebrates:

A new study shows an ingredient found in red wine, which has previously shown to prolong the life of worms and fruit flies, may extend the lifespan of vertebrate animals like fish and possibly humans.

Researchers found adding resveratrol, an organic compound found in grapes and particularly in red wine, to the daily diet of short-lived fish prolonged their lifespan and delayed the onset of age-related memory and other problems...

In this study, published in Current Biology, researchers examined the effects of resveratrol on a small type of fish that lives only three months in captivity.

The results showed that adding the red wine ingredient to the daily diet of the fish prolonged their expected life span and slowed the progression of age-related memory and muscular problems.

Researchers found fish fed the lower dose of resveratrol lived an average of 33% longer than fish fed their normal diets, while those fed the higher dose of the red wine ingredient lived more than 50% longer.

An abstract of the original article can be found here, but it doesn't mention the specific statistics quoted above (which admittedly sound conveniently fractional).

I've been taking resveratrol for about a year now. Not that I'm an expert, but Longevinex seems like the best brand out there. Interestingly, they have a good bit of detail on the study -- more than in any of the news stories I found:

Researchers continue to demonstrate, in higher life forms, that lifespan is increased with the feeding or resveratrol, widely known as a red wine molecule. The most recent report, involving killfish, the highest life form yet to be tested, reveals increases in lifespan ranging from 27-59% when research-grade resveratrol was added to fish food. Lifespan was increased in a dose-dependent manner in this species of fish that has the shortest median lifespan of any vertebrate, about 9 weeks.

Equally remarkable was the impact resveratrol had on the quality of life of killfish. After 50 passes through a shuttle-box learning test, 73% of the time young fish navigated the test compared to just 42% success rate among old fish and a remarkable 74% success rate among old fish fed resveratrol! Researchers in Italy who conducted the study said "resveratrol-fed fish showed remarkable preservation of learning and prevention of age-related brain degeneration."

The jury is still out, obviously. A study of resveratrol's effects on mice will provide the first look at its effectiveness on mammals. But so far, to the best of my knowledge, every species studied has shown significant lifespan gains with resveratrol. That's good enough for me, for now, at least.


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